Reference Intervals for Blood Biomarkers in Farmed Atlantic Salmon, Coho Salmon and Rainbow Trout in Chile: Promoting a Preventive Approach in Aquamedicine

Marco Rozas-Serri, Rodolfo Correa, Romina Walker-Vergara, Darling Coñuecar, Soraya Barrientos, Camila Leiva, Ricardo Ildefonso, Carolina Senn and Andrea Peña Abstract The mission of veterinary clinical pathology is to support the diagnostic process by using tests to measure different blood biomarkers to support decision making about farmed fish health and welfare. The objective of this study […]

Why Does Piscirickettsia salmonis Break the Immunological Paradigm in Farmed Salmon? Biological Context to Understand the Relative Control of Piscirickettsiosis

Marco Rozas-Serri Abstract Piscirickettsiosis (SRS) has been the most important infectious disease in Chilean salmon farming since the 1980s. It was one of the first to be described, and to date, it continues to be the main infectious cause of mortality. How can we better understand the epidemiological situation of SRS? The catch-all answer is […]

Full recombinant flagellin B from Vibrio anguillarum (rFLA) and its recombinant D1 domain (rND1) promote a pro-inflammatory state and improve vaccination against P. salmonis in Atlantic salmon (S. salar)

Roxana González-Stegmaier, Andrea Peña, Franz Villarroel-Espíndola, Patricia Aguila, Cristian Oliver, Desmond MacLeod-Carey, Marco Rozas-Serri, Ricardo Enriquez, Jaime Figueroa. Abstract Flagellin is the major component of the flagellum, and a ligand for Toll-like receptor 5. As reported, recombinant flagellin (rFLA) from Vibrio anguillarum and its D1 domain (rND1) are able to promote in vitro an upregulation of pro-inflammatory genes […]

Cost-effectiveness of longitudinal surveillance for Piscirickettsia salmonis using qPCR in Atlantic salmon farms (Salmo salar) in Chile

Marina Delphino, Fernando Mardones, Joaquin Neumann, Alicia Gallardo, Daniel Jimenez, Andrea Peña, Marco Rozas-Serri, Ian Gardner Abstract Costs of diagnostic testing including sample collection, sampling frequency and sample size are an important consideration in the evaluation of the economic feasibility of alternative surveillance strategies for detection of infectious diseases in aquatic animals. In Chile, Piscirickettsia salmonis […]

Bayesian estimation of diagnostic sensitivity and specificity of a qPCR and a bacteriological culture method for Piscirickettsia salmonis in farmed Atlantic salmon (Salmo salar L.) in Chile

Emilie Laurin, Ian Gardner, Andrea Peña, Marco Rozas-Serri, Jorge Gayosa, Joaquin Neumann, Fernando Mardones Abstract Early detection of piscirickettsiosis is an important purpose of government- and industry-based surveillance for the disease in Atlantic salmon farms in Chile. Real-time qPCRs are currently used for surveillance because bacterial isolation is inadequately sensitive or rapid enough for routine use. […]

Atlantic Salmon Pre-smolt Survivors of Renibacterium salmoninarum Infection Show Inhibited Cell-Mediated Adaptive Immune Response and a Higher Risk of Death During the Late Stage of Infection at Lower Water Temperatures

Marco Rozas-Serri, Carlos Lobos, Rodolfo Correa, Ricardo Ildefonso, Jorge Vásquez, Ariel Muñoz, Lucerina Maldonado, Victoria Jaramillo, Darling Coñuecar, Camila Oyarzún, Romina Walker, Carolina Navarrete, Jorge Gayosa, Patricio Mancilla, Andrea Peña, Carolina Senn, Francisco Schwerter Abstract Bacterial kidney disease (BKD) is widespread in many areas of the world and can cause substantial economic losses for the salmon aquaculture industry. The […]

Gene expression associated with immune response in Atlantic salmon headkidney vaccinated with inactivated whole-cell bacterin of Piscirickettsia salmonis and pathogenic isolates

Marco Rozas-Serri, Andrea Peña, Lucerina Maldonado Abstract Piscirickettsiosis is the most challenging disease present in the Chilean salmon industry. The aim of this study was to describe the expression of genes associated with immune response of Atlantic salmon intraperitoneally infected with LF-89 and EM-90 Piscirickettsia salmonis and vaccinated with inactivated whole-cell bacterin of P. salmonis. […]

Gill diseases in marine salmon aquaculture with an emphasis on amoebic gill disease

Marco Rozas-Serri Abstract Gill diseases are a growing health challenge in salmon farming worldwide, but many gaps remain in our knowledge. Gill diseases are generally complex and multifactorial disorders, often with presumable spatial and temporal distribution patterns, but are highly difficult to effectively prevent and control. The term complex gill disease (CGD) includes a wide […]

Transcriptomic profiles of post-smolt Atlantic salmon challenged with Piscirickettsia salmonis reveal a strategy to evade the adaptive immune response and modify cell-autonomous immunity

Marco Rozas-Serri, Andrea Peña, Lucerina Maldonado Abstract Piscirickettsiosis is the main bacterial disease affecting the Chilean salmon farming industry and is responsible for high economic losses. The development of effective strategies to control piscirickettsiosis has been limited in part by insufficient knowledge of the host response. The aim of this study was to use RNA […]

Comparison of gene expression in post-smolt Atlantic salmon challenged by LF-89-like and EM-90-like Piscirickettsia salmonis isolates reveals differences in the immune response associated with pathogenicity

Marco Rozas-Serri, Andrea Peña, Gabriel Arriagada, Ricardo Enríquez, Lucerina Maldonado Abstract Piscirickettsiosis is the main bacterial disease affecting the Chilean salmon farming industry and is responsible for high economic losses. The aim of this study was to describe and comparatively quantify the immune response of post-smolt Atlantic salmon infected by cohabitation with fish bearing LF-89-like […]